At the Institute of Pharmaceutical Sciences (TIPS)’s journal club meeting held online on April 12, 2021, the topic of “Biosimilar” was presented by Sh. Golshani. In this meeting, biosimilar as the opportunity to develop generic substitutes for original biologicals was presented. The complex process of introducing a biosimilar to an innovator product including verification of the similarity, the fungibility of biosimilars, regulatory framework, commercial opportunities, guidelines to assist manufacturers in product development and safety were introduced.